The effect of chondroprotectors on the whole. Chondroprotectors for joints. List of drugs of the new generation. The most effective for osteochondrosis of the spine, arthrosis. With extracts of medicinal plants

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Date of: 2017-03-06 Views: 38 424 Grade: 5.0 I have already talked about drugs that improve the nutrition of articular cartilage. The most common class of them are chondroprotectors (chondroitin and glucosamine preparations). There are probably hundreds of brands of such supplements on the modern pharmaceutical and sports nutrition market. Many of them are only positioned as effective, and the drug is “pumped up” with a bunch of extra components, if only the composition on the label is full of incomprehensible terms. I want to make one point right away. At the last congress of rheumatologists, it was found that a truly effective chondroprotector should contain at least 1500 mg and 500 mg in a daily dose. . In addition, the presence of collagen in the preparation is desirable. Next, we will consider the composition of the most popular chondroprotectors so that you can choose the one you need yourself. The combined use of additives is not excluded. I have provided the information in the form of a table to highlight only the really "working" components.

Name of the drug	Collagen mg.	Glucose- amine mg.	Chondro- itin mg.		vitamins And minerals	Additional Components	Daily dose and long-term course.
Geladrink Forte	8000	1500	800		Vit. WITH Vit. E manganese selenium.	MSM - 600 mg. Boswellia extract - 100 mg.	14 gr. Or 12 cap. 2 months
Geladrink Plus	9500	200	100		Vit. WITH, Vit. E, biotin, manganese selenium. calcium, magnesium	MSM - 100 mg.	12 gr., 2 months
Artranov	390	300	150		Vit. WITH, Vit. E, Vit. D3, phosphorus, manganese selenium, calcium	Boswellia extract - 90 mg., Turmeric - 30 mg.	3 cap., 2 months
Collamin 80	The additive is not registered on the territory of the Russian Federation.
Glucosamine AJF		600	300			shark cartilage extract	2 cap., 2 months
Osteomax - Premium		420	120		Vit. WITH, Vit. AT 6, Vit D3, calcium, magnesium, manganese zinc		3 cap., 6 months
Arthrostop Plus		1000			manganese		2 tab., 1 month
Arthritosamine Helenpro		1500	600		Vit. E		3 tab., 2 months
Chondronorm		500	300		Vit., B1, B6, B12, zinc, copper, salicin		2 drops, 1 month
Don		1500					1 pack, 2 months
Structum			1000				2 cap., 6 months
Artra		1500	1500				3 tab., 6 months
Teraflex		1500	1200				3 tab. 6 months
Glucosamine Sulfate		1500					2 tab., 6 months
ArtroFlex		1500	1050				4 tab., 1.5 months
HONDROnova		1500	1200				6 cap., 2 months
Artron		1500	1500				3 tab. 2-3 months
Glucosamine-chondroitin complex		750	375				5 tab. 3-4 months
Inoltra		1000	200		Vit. WITH Vit. E	Omega 3,6,9	3 cap. 3 months
Honda		400	400		Calcium	burdock root extract, White Willow Bark Extract	4 cap., 6 months
Maxler: Glucosamine Chondroitin MSM		1500	1200		calcium, magnesium, silicon	MSM - 1200 mg.	3 cap., 2 months
SAN: Glucosamine Chondroitin with MSM		1500	1200		calcium, magnesium	MSM - 1200 mg.	3 cap., 2 months
Universal Nutrition: Animal Flex		3000			Vit. WITH Vit. E manganese selenium, zinc	Omega 3 MSM Hyaluronic acid boswellia extract, Bromelain quartzetine	1 pack 2-4 months
BioTech: Glucosamine Chondroitin		605		400	Calcium magnesium		4 cap., 3-4 months

Thus, Geladrink Forte, Arthritosamine Helenpro, Artra, Teraflex, CHONDRONOVA, Artron, as well as supplements from SAN, Maxler and Universal Nutrition are acceptable in composition. There is one more nuance, of all the listed drugs, only Artra and Teraflex are registered in the Russian Federation precisely as medicines, i.e. only their composition is laboratory tested. Nevertheless, I use sports supplements in my practice, because I consider them more complex. Recently, I have been using Geladrink Forte more often. Not a bad price for a monthly course (about 2700 rubles). It is easier to take in powder (I usually divide the daily dosage into 2 doses: 7 grams each in the morning and evening). Also good reviews about Animal Flex and Elasti Joint from Labrada. Be that as it may, the final choice is still yours. The main thing to remember: increased stress on the joint requires enhanced nutrition for cartilage tissue. Therefore, with active sports (even if nothing bothers you), be sure to take courses of chondroprotectors at least 1 time per year.

Only now the question arises, if this is such a necessary and irreplaceable thing, how did our grandmothers-great-grandmothers wait until 90-100 years old, run with their own legs, and manage around the house and in the garden without helpers, but we never heard of these miracle supplements heard?

That's what I think - if you eat normally, but move in moderation, then there will be no health problems, and all diseases are due to idleness!

What are chondroprotectors for?

Most degenerative pathologies of the supporting apparatus are characterized by the destruction of cartilage, which ultimately leads to severe pain and limited mobility. Therefore, specialists often prescribe chondroprotectors for joints to people with such problems.

However, it must be remembered that the sooner treatment begins, the more effective it will be. In the later stages of the disease, these drugs are already useless.

These drugs contribute to the active restoration and preservation of the integrity of the cartilage. Naturally, they will not help in one day, so the course of therapy lasts at least 2 months. Chondroprotectors contain components such as: glucosamine and chondroitin sulfate. In addition, tablets may contain additional substances: antioxidants, minerals, vitamins.

Chondroprotectors are drugs that act exactly in the place where the problem is localized. The active substances that are in the composition of the presented funds help to reduce the amount of effusion in the joint bag.

And yet, taking the medication reduces the intensity of the inflammatory process, improves the general condition of the porous cartilage tissue. Due to this, the intensity of pain gradually decreases. A feature of chondroprotectors is that they do not contribute to the formation of new tissues, but to the restoration of old cartilage.

However, there will be a positive effect only if the affected joint still has at least a small layer of cartilage.

Chondroprotectors can be taken in conjunction with analgesics. With deforming diseases of the locomotor apparatus, tablets of this type can be effective only when the pathology is at the very beginning of its development. Moreover, the treatment process is not very short.

Main active ingredients

Chondroprotectors - drugs that affect the structure of cartilage, containing glucosamine, chondroitin and other components. Briefly about the components.

Glucosamine is involved in the creation of connective tissue, bones, skin and tendons, as well as in the formation of intra-articular fluid. In addition to the chondroprotective action, it also exhibits anti-inflammatory, antihypoxic, hepatoprotective, detoxification activity.

With the systematic use of glucosamine

the process of damage to the joints and spine slows down;
stimulates own production of glucosamine in the joints;
pain decreases;
increased joint mobility.

The result of the application is manifested from several weeks to six months. Chondroitin for joints preserves and forms cartilage and bone tissue, accelerates the restoration of cartilage. Maintains the viscosity of the synovial fluid. It is part of the intra-articular lubrication. With systematic use, it slows down the progression of osteoarthritis, relieves pain in osteoarthritis, and reduces the need for NSAIDs.

Methylsulfonylmethane (MSM) is also essential for healthy joints. This substance is an organic source of sulfur. Sulfur is needed for skin, nails, hair. MSM connects the collagen fibers of the joints, strengthens bone and cartilage tissues, reduces pain in the muscles and joints.

The complex action of MSM, chondroitin and glucosamine is aimed at increasing the therapeutic effect in arthritis, sprains, bursitis, arthrosis, bone fractures, etc.

It is advisable to use combined chondroprotectors in the prevention and treatment of joint diseases. This is due both to the economical side - there is no need to purchase several mono-drugs, and to clinical studies.

Classification of chondroprotectors

In general, there are several classifications of the presented products. The first of these is based on the "age" of the drug:

First generation drugs - Alflutop and Rumalon.
The second generation drugs include drugs based on hyaluronic acid, glucosamine and chondroitin sulfate.
Third generation drugs include hydrochloride in combination with chondroitin sulfate.
Chondroprotectors of a new generation.

Another classification is formed on the basis of those components that make up the chondroprotector:

Preparations, the main component of which is chondroitin: "Honsulid", "Chondrolon", "Mukosat", "Artron", "Strukturum", "Chondrex".
Products based on the natural extract of animal or fish cartilage: "Rumalon", "Alflutop".
Mucopolysaccharides: "Arteparon".
Means containing glucosamine: "Don's drug".
Complex medicines: "Teraflex", "Artron complex".

The remedy "Artrodar" is quite effective, since in addition to the restoring effect it also has an anti-inflammatory effect.

In addition, there is a classification of chondroprotectors, which is based on the form of their release:

Tablets or capsules for oral administration: "Artra", "Don", "Struktum", "Teraflex", "Piaskledin". A feature of the funds presented is that they begin to act only after 2-3 months. However, after 6 months, a stable effect is observed. Despite the fact that chondroprotective drugs have to be used for a long time, they are usually well tolerated by the body and do not have side effects.
Medicines for injection: Moltrex, Elbona, Adgelon, Alflutop, Chondrolon. Any of these chondroprotectors is more effective than tablets or capsules, as it acts much faster. In this case, intramuscular injection of the drug is used. The patient has to take a course of injections, which is 10-20 injections, after which he is prescribed pills.
Substitutes for the fluid that is inside the joint: "Ostenil", "Synokrom", "Synvisk", "Fermatron". They are used for direct injection into the joint. In general, the course of therapy in this case is 3-5 injections, but sometimes even one injection has the desired effect. If there is a need to repeat the course of therapy, then this can be done no earlier than after 6 months.

As you can see, chondroprotectors are different, so you should not buy and take them yourself. Before starting treatment, you must always consult with your doctor. In each case, the drug is selected individually.

New generation drugs

Chondroprotectors for the joints of the new generation are distinguished by their versatility, as they have a large spectrum of action. The fact is that these products include auxiliary components and vitamins, due to which the degree of exposure increases, and the level of toxicity decreases. The benefits also include:

They are easier to perceive by the body and, as a result, are tolerated by patients.
The most pronounced therapeutic effect.
Side effects are practically absent.
Equally effective in all degrees of severity of diseases.
The mechanism of action on cartilaginous tissues is diverse.
Additionally, they have a powerful anti-inflammatory effect.
Anesthetize quickly.
They have a pathogenic effect.
Enhance the effectiveness of other drugs.
Increase bone and cartilage density.

Chondroprotectors for the new generation joints can be very different, in particular, 3 groups of similar drugs can be identified, namely such as:

products based on hyaluronic acid;
preparations containing plant extracts;
means, which include a transport system.

However, it is worth remembering that despite the fact that chondroprotectors have a fairly good effect on the damaged joint, they can only be effective in the initial stages of the disease, since if the joint is destroyed, then surgical intervention is required.

Chondroprotectors for joints of the new generation are guaranteed to provide the required therapeutic effect in the shortest possible time, and they also provoke much fewer side effects and various complications.

Products with hyaluronic acid

Hyaluronic acid is the main component of the joint fluid. It gives it additional density, and is also guaranteed to ensure the normal sliding of cartilage. New generation chondroprotectors containing hyaluronic acid are among the most common drugs.

If there is inflammation, then it is initially eliminated with the help of anti-inflammatory drugs or hormones, and then the joint is treated with hyaluronic acid. The list of such drugs includes:

Fermatron;
Suplasil;
Ostenil;
Hyalgan fidia.

Fermatron is characterized by the fact that its composition contains an active substance, an analogue of the natural joint fluid. This drug is available in the form of injections that are injected directly into the joint cavity.

Fermatron contributes to the rapid elimination of pain, relieves the inflammatory process, and also helps the production of natural hyaluronic acid, while restoring cartilage tissue and joint mobility. To complete the full course of therapy, it is enough to make 5 injections, one per week.

Hyalgan fidia is an aqueous solution of the salt composition of hyaluronic acid. This is a fairly good medicine that helps stimulate joint recovery and reduces pain. The agent is injected into the joint once a week for 5 weeks. This remedy is forbidden to be used for violations of the liver, and it is also not used to treat children.

The drug Suplazin is considered a kind of substitute for natural joint fluid. Its active substance is part of hyaluronic acid. It helps to maintain the desired function and activity of the joint and provides the desired analgesic effect. This remedy is injected directly into the joint cavity. The course of therapy is 3 procedures, 1 injection once a week.

Ostenil is an aqueous solution of sodium salts. This is a fairly good and effective tool that helps:

activate the mechanisms for restoring joint mobility;
promotes the formation of natural joint fluid;
removes the inflammatory process.

Ostenil is used in the form of injections that are injected into the articular cavity. It is necessary to make 3-5 injections with breaks of 7-10 days.

With extracts of medicinal plants

New chondroprotectors with extracts of medicinal plants help to quickly restore joint mobility, reduce inflammation and eliminate existing pain. A striking example of this group of chondroprotectors is Piascledin. This product contains soybean and avocado oil. Due to the presence of such components, such a drug contributes to:

collagen synthesis;
restoration of joint structures;
a decrease in the production of enzymes that destroy cartilage tissue;
elimination of inflammation and pain.

Piascledin comes in the form of capsules. However, it is worth remembering that this remedy may have certain contraindications, so you should first consult with your doctor regarding their use.

With transport system

The introduction of modern chondroprotectors of the latest generation through the skin is considered a fairly good method of therapy. In most cases, special equipment is used for this, since otherwise the active substances will penetrate only into the upper layers of the skin.

A fundamentally new method of conducting therapy is the introduction of chondroprotectors using a special transport complex. It helps to deliver drugs through the skin, muscles, mucous membranes and bones.

The list of such drugs is not very large, however, they are quite effective and of high quality. Hyalgel belongs to the means that contribute to the rapid restoration of damaged cartilage structures.

It helps to eliminate the inflammatory process and reduce pain. The composition of this remedy includes tizol, which not only effectively conducts medicinal substances, but also eliminates the inflammatory process. Due to the gel structure of the product, it does not provoke the occurrence of edema and does not interfere with the natural penetration of oxygen.

Hyalgel should be applied to the skin in the area of the joints 1 time every 2-3 days. The course of application of this tool is 4-8 times. This drug has a minimum number of side effects, and it also has shorter periods of therapy.

What diseases are treated?

Among the causes of pathologies of the musculoskeletal system, a special place is occupied by

transferred infectious diseases that directly affect the joints;
sedentary lifestyle;
significant physical activity during professional activities;
insufficient content in the diet of substances that the body uses to restore cartilage and connective tissue and their normal functioning.

It is also worth noting the age factor, since with age the body's ability to independently produce natural substances - glucosamine and chondroitin, which are the main components of synovial fluid, decreases. The most common diagnoses are arthritis, arthrosis or osteochondrosis.

These diseases are manifested by various clinical manifestations. Joint pain that occurs during or after exercise the appearance of limited range of motion and local morning stiffness.

Aching night pain becomes constant. There is a crunch in the joint when moving; decreased range of motion in the affected joint; the shape of the joint changes and pain is manifested during its palpation. Sinuvit appears - swelling and redness of soft tissues in the area of the knee joints, interphalangeal joints of the hand.

Basically, the cause of these symptoms lies in the destruction of the articular cartilage. The reason for the destruction of cartilage tissue is a mismatch between the mechanical load on the articular cartilage (or intervertebral disc) and its ability to resist this load.

The cartilage gradually loses its ability to retain fluid, which leads to a decrease in firmness and elasticity, becomes unevenly thinner, and deep cracks form in it. Cartilage, which is adjacent to the bones and forms a natural cushion between them, becomes thinner when moving. Over time, cartilage loses its elasticity and strength.

The main goal of prevention and drug therapy is to prevent the destruction of articular cartilage, so the regular use of chondroprotectors is advisable and rational.

Coxarthrosis. This is a disease in which physiological wear of the joint occurs and its functional activity is limited.

For its treatment, chondroprotectors are prescribed, which include chondroitin sulfate and glucosamine. The drug of choice is Teraflex. It not only stimulates cartilage regeneration and the production of a healthy matrix, but also provides protection against cartilage damage.

When treated with this chondroprotector, the need for non-steroidal anti-inflammatory drugs is significantly reduced. In addition to Teraflex, Chondroxide is often prescribed in the treatment of coxarthrosis. It stimulates the regeneration of the articular bag and improves the metabolism in fibrous and hyaline cartilage.

Osteochondrosis. A disease in which intervertebral discs are affected together with the ligamentous apparatus of the spine and adjacent vertebral bodies.

For the treatment of this disease, drugs are used that help restore the cartilage tissue of the intervertebral joints and reduce pain. These are mainly Dona, Artra and Structum.

In the treatment of osteochondrosis, it is especially important to start treatment as early as possible; in advanced cases of the disease, chondroprotectors are practically useless.

In addition, they should be used simultaneously with other drugs - non-steroidal anti-inflammatory drugs (Diclofenac, Voltaren) and vitamin complexes (Milgamma). The scheme of taking drugs and their combination should be selected by the doctor after a thorough examination.

arthrosis. This is a dystrophic change in the articular surfaces of a chronic nature. There are many both positive and negative reviews about the effectiveness of the use of chondroprotectors in this disease.

It should be noted that positive dynamics is observed only at the beginning of treatment in the early stages of the disease and if the drugs are taken for a long time. The drugs of choice in this case are mainly Artron flex, Dona, Teraflex and Alflutop. They improve the lubricating properties of the intra-articular fluid and stimulate its production.

Diseases of the spine. Chondroprotectors are prescribed for vertebral arthritis, spondylosis, osteochondrosis, spinal injuries and in the postoperative period. The most commonly used Alflutop, Rumalon, Artrodar (complex drug) and other drugs prescribed by a doctor.

Since the disease of the spine destroys the cartilage tissue and reduces the interarticular fluid, the main task of chondroprotectors for the joints is to normalize the physiological composition of the cartilage tissue, thereby contributing to its restoration. This reduces the swelling of the joints, their stiffness and the intensity of pain.

Another action of chondroprotectors is the normalization of the composition and amount of synovial fluid. This helps restore joint function and strengthen cartilage.

Chondroprotectors also have an anti-inflammatory effect. But this effect appears after 2 - 3 weeks after the start of treatment and it lasts for quite a long time. This is what distinguishes chondroprotectors for joints from other anti-inflammatory drugs.

Arthritis. Inflammatory disease leading to malnutrition of the joint. In its treatment, chondroprotectors are used together with painkillers and anti-inflammatory drugs. Prescribed mainly drugs containing chondroitin sulfate and glucosamine. These are Structum, Dona, Artron flex and Chondroxide.

Such treatment leads to a decrease in pain and swelling, and joint mobility returns. In case of damage to large joints (knee), chondroprotectors are introduced into the joint.

Brief description of popular drugs

The following drugs can be distinguished for the treatment and restoration of joints:

Don. This is a modern drug, the main component of which is glucosamine sulfate. It has a positive effect on the metabolic processes occurring in the cartilage. In addition, the remedy is able to relieve inflammation, and, therefore, pain. It is usually used for osteochondrosis, arthrosis, arthritis. The powder is taken once a day for at least 6 weeks.

If it is necessary to use the injection route of administration, then it is necessary to use one ampoule every other day. The course of therapy is a month and a half. The effect is felt in a couple of weeks. Price 1400–1500 r.

Teraflex. The product contains chondroitin and glucosamine. The product is used for osteochondrosis, arthrosis, sports and household injuries. These tablets should not be taken by people with phenylketonuria. The action of the product is aimed at stimulating the regeneration of cartilage. This chondroprotector is used for at least 3 weeks. The main form of release of the presented agent is tablets. Despite the effectiveness of the drug, it is forbidden to use it on its own. Price 1400–1500 r.

"Artra". It is a very effective pharmaceutical product and is considered one of the very best. The product contains both chondroitin and glucosamine. The drug is used for osteochondrosis and arthrosis. Do not use the remedy for the treatment of children under 15 years of age, as well as those people who suffer from kidney failure. In addition, there are some restrictions on use, so the instructions should be read before starting treatment. Price 2100–2200 r.

"Rumalon". This is a natural preparation for the treatment of joints, which is produced on the basis of bone marrow and cartilage tissue of calves. Most often, the medicine is used for necrosis of the cartilage of the patella, spondylarthrosis, spondylosis. Due to the fact that the composition of the product contains natural ingredients, it can cause allergic reactions, so you need to be careful when using it. Price 1600–1700 r.

"Structum". The main active ingredient of the product is chondroitin sulfate. Not everyone can take it, so it's best to consult a doctor first. Price 1400–1500 r.

"Piaskledin". The presented chondroprotector is involved in the metabolism in the cartilage, which makes it possible to slow down the degenerative processes in the joints. The drug makes it possible to reduce the intensity of pain, stimulates the production of collagen. It can help restore normal joint mobility. Price 1200–1300 r.

Alflutop. This is a natural chondroprotector, which is made from the cartilage of some types of fish. It takes about 20 days to be treated with this remedy. Periodically, the course of therapy is repeated. The price is 1500–1900 rubles, depending on the amount of solution.

"Artradol". This is a domestic medicine that regulates metabolic processes in cartilage tissue, promotes its regeneration, and prevents destructive processes affecting connective tissue. Price 650–900 rubles.

"Mukosat". This chondroprotector for the treatment of joints is sold in ampoules so that chondroprotectors for joints can be injected. A remedy is prescribed for osteoarthritis, periodontopathy, osteoporosis. Naturally, an important condition for a positive effect is the degree of development of joint pathology. The price is 350–700 rubles, depending on the amount of the solution.

"Toad Stone". This product cannot be called a drug. It is considered a dietary supplement that can be bought in the form of capsules and ointments. The course of treatment is a month. The price of the ointment is 50–60 rubles.

Chondroxide is a popular ointment or tablet that is used to normalize cartilage metabolism, reduce pain intensity, and increase joint mobility. The drug is characterized by the fact that it provides a lasting effect. The ointment also relieves inflammation. The price is 400–950 rubles, depending on the form of release.

"Formula C". This tool is used for the prevention and treatment of joint pathology. Most often, the product is not used independently.

"Tramel". This natural homeopathic preparation, which not only relieves inflammation, but also strengthens the immune system, regenerates cartilage tissue. This chondroprotector is sold as an ointment, injection liquid and tablets. Price 400–750 rubles.

"Hyaluron". The tool accelerates the regeneration of hard tissues of the joint. "Noltrex" is a new name in the "family" of chondroprotectors. It is a synthetic polymer that comes in the form of an injection liquid. The composition of the product contains silver ions, therefore it provides an antibacterial effect. Price 3000–4000 r.

This list of chondroprotectors is far from complete. However, these funds are considered the most famous. The action of chondroprotectors has the following features:

slow effect - after 6 months after the start of therapy;
exposure at the initial stage of the disease, when the cartilage does not regenerate.

Chondroprotectors injected into the joint are based on fermatron, synvisc, synokrom, ostenil. Injections are intra-articular fluid substitutes injected into a large joint: knee or hip. The course of therapy with injections lasts up to 5 injections for 6 months. Sometimes a single entry is shown.

In case of arthrosis of the hip joint, drugs are introduced similar to those in the case of damage to the knee joint. But the treatment is carried out under the control of the x-ray machine. With coxarthrosis, 2-4 courses of treatment are prescribed for 6 months.

With spondylarthrosis, the state of the cartilage changes, so Rumalon, Edbon, Structum are prescribed. If the compositions of the hands are affected, chondroprotectors are effective if the disease is at an early stage. Patients with this diagnosis are prescribed glucosamine sulfate. It improves joint lubrication. Some patients are prescribed Traumeel, Alflutop.

Any medicinal ointment or tablets should only be used as directed by a doctor. The fact is that the list of drugs is very large, each of them contains various active ingredients. Some of them provoke an allergic reaction. In addition, you need to know what contraindications to use exist.

In the early stages of the development of the disease, as well as during remission, local preparations, as well as tablets or capsules, can help. If the patient has an allergic reaction to chondroprotectors, then it is better not to use first-generation drugs. In this case, a more modern tool is used.

If therapy involves the course use of chondroprotectors, then the intake of different dosage forms should be consistent. The duration of therapy depends on the degree of development of the disease, the characteristics and response of the body to treatment, and is determined individually.

In order for chondroprotectors for joints to be more effective, they must be taken even in the early stages of the development of the disease. In addition, the patient should also follow some recommendations:

It is advisable to reduce body weight if it is significantly more than normal. Otherwise, the deformation of the joints under the influence of a very large load will only intensify. It is important to consult a nutritionist here, as nutrition should be balanced.
Do not load the affected joint too much.
Physical therapy can help restore joint mobility, but a set of exercises is selected individually.
Hiking on flat terrain is considered very useful.
We must not forget about the rest.
Hypothermia of the lower or upper extremities should not be allowed.
Only in this case, the treatment of diseases of the supporting apparatus can be effective.

What dosage form is most effective?

Only a qualified doctor can determine the specific form in which the drug will be taken. More often, therapy begins with intramuscular or intraarticular injections. Then the injections are replaced with internal preparations, external ointments, gels.

From injection solutions appoint:

Adgelon;
Hondrolon;
Elbon.

Intramuscular solutions act faster, producing a better effect than tablets and ointments. Injection therapy is carried out in a course of 10-12 injections.

Tableted chondroprotectors act slowly, producing their effect 3 months after the start of treatment. A stable effect of the tablets is observed 6 months after the start of treatment.

With the help of ointments and creams, swelling and inflammation of the joint are removed, pain is reduced, and tissue regeneration is stimulated. For external therapy, Traumeel, Chondroxide, Horsepower are prescribed. If the blood got into the bag, the patient is prescribed Traumeel gel or ointment. Therapy with external means is carried out at the initial stages of the disease. Treatment lasts up to six months, less often up to 3 years.

Help in choosing the best drug for the joints

Modern pharmaceutical companies offer chondroprotectors for the joints in the widest range, which provides each patient with the opportunity to easily choose the optimal form of release of the medicinal product for an individual treatment program.

Before starting a course of cartilage tissue regeneration, it is recommended to consult a doctor, which will allow you to objectively assess the patient's condition and determine the presence of contraindications to taking certain drugs.

stage of the disease (drugs to restore the strength and elasticity of cartilage are effective only in the early stages of the pathological process);
presence of indications and contraindications;
form of release of the medicinal product;
pharmaceutical company;
method of application and composition of the chondroprotector.

The active substances of chondroprotectors act in two directions: they help the body restore the connective tissue of cartilage, ligaments, tendons and joint fluid, and retain water in the thickness of the cartilage, creating the necessary cushioning to absorb shocks. In addition, they have analgesic and anti-inflammatory properties.

Thus, preparations for the joints and cartilage of the new generation help to alleviate the condition as much as possible and speed up recovery, and are also an effective tool for the prevention of diseases of the musculoskeletal system.

Despite the fact that these drugs have practically no side effects, there are a number of contraindications for their use. The active substances that make up these drugs can have completely different effects.

In this regard, the use of such drugs is not recommended during pregnancy and lactation. In addition, you should not use them in the presence of an allergic reaction, diabetes and diseases of the gastrointestinal tract.

There may be other risks of using this therapy, which is why you first need to consult a doctor regarding the advisability of taking them.

The opinions of doctors about taking chondroprotectors are very different, as there are supporters and opponents of taking such drugs. Many believe that they cannot provide instant results. In addition, there is an opinion that the desired effect from the use of these drugs may not be, since everything depends on the degree of progression of the disease and the characteristics of the organism.

Chondroprotectors combine a wide group of supplements, the main purpose of which is to protect the joints. Most often, the main active ingredients in the composition of chondroprotectors are glucosamine and chondroitin sulfate.

Preparations for the joints of the new generation Chondromarin and Chondromarin Cryptos, presented on this page, are fundamentally different from the "classic" chondroprotectors in that 1) they also contain oligonucleotides and enzymes, 2) the preparations are created using Axis technology, which allows chondroprotectors in tablets to be absorbed with exactly the same degree of effectiveness as drugs in injections (that is, injections are no longer needed!).

What are oligonucleotides in the composition of the chondroprotector Chondromarin and what is the effect?

Oligonucleotides are a "finely shredded" DNA molecule, a valuable substance of natural origin, which is a building material for our own cells, especially for diseased (damaged) cells of our body during periods of chronic diseases. Oligonucleotides have an anti-inflammatory effect, restore metabolism, suppress autoimmune processes (which is very important in autoimmune diseases such as arthritis).

Effects of oligonucleotides and enzymes: necrolytic (destruction of proteins of non-viable damaged cells), thrombolytic (destruction of formed vascular thrombi), mucolytic (expectorant), diuretic (diuretic). Preparations clear the vessels, remove inflammation and remove toxins.

It is thanks to oligonucleotides that the pathways are “cleared” for the delivery of nutrients to the inflamed joint. Ordinary chondroprotectors in tablets cannot cope with this task.

Cutting a DNA molecule to the level of oligonucleotides is a very expensive process, it is a nanomolecular technology. However, without the use of Axis technology, the use of oligonucleotides would not make any sense. The fact is that the gastrointestinal tract is an aggressive environment for enzymes, and without special treatment, the effectiveness of tableted enzymes is close to zero. Axis-technology is a patented development of the Siberian Center for Pharmacology and Biotechnology, which allows you to deliver active ingredients to the blood without loss of efficiency. This is actually a revolution in pharmacology, since almost any injectable drugs can now be converted into tablets without losing their effectiveness.

Actions of chondroitin sulfate as part of chondroprotectors:

accelerates the formation of cartilaginous elements;
protects joints from destruction;
fights inflammation;
activates the synovial fluid that fills the cavity of the articular elements.

Actions of glucosamine:

prevents the effects of damaging factors (for example, free radicals);
neutralizes inflammation, relieves swelling;
synthesizes the components necessary for the development of cartilage tissue.

Preparations chondroprotectors are concentrated on the restoration and elimination of cartilage tissue defects. They prevent inevitable changes, normalize processes in the body. The composition contains elements that ensure the normal operation of the synovial fluid used as a lubricant.

When cartilage breaks down, rough bone tissue is exposed. In contact with the bone, the opposite cartilage is deformed. Synovial fluid is not produced, and the joints are no longer lubricated. This leads to their deformation. If you start taking the drug in time, the intra-articular fluid returns to normal, and the damaged cartilage is restored.

Chondroprotectors are long-term agents with a cumulative effect. They are especially effective at the initial stage of destruction.

How to use

The course of application is prescribed by a doctor. It usually takes 2-3 courses to stop deformation processes. On average, therapy lasts 2 months, then it needs to be repeated. The use of chondroprotectors in case of serious damage to bone tissue can take 0.5-2 years. Contraindicated in case of individual intolerance.

Chondroprotectors for joints are available in the form of:

solutions for injections;
capsules, tablets and powders for oral administration.

Chondroprotectors in injections

The drugs are injected directly into the joint tissue or muscle.

Intramuscularly: enter the blood. To achieve a positive effect, you first need to relieve vasospasm;
intra-articular: there are two types - conventional and replacing synovial fluid. This is the most effective way: the tool instantly moisturizes the cartilage surface and removes friction.

Disadvantages of chondroprotectors in injections:

The impossibility of injecting into each individual small joint (for example, with polyarthritis of the joints of the hands, characterized by multiple lesions of small joints)
Soreness of the procedure
Each injection in each joint must be given at least 7-10 times (course intake)
The high cost of funds.

Chondroprotectors in tablets

The chondroprotectors presented on this page are fundamentally different from most tableted chondroprotectors. As mentioned above, these drugs are processed using Axis technology, which allows you to increase the effectiveness of the chondroprotector in tablets to the level of the effectiveness of the injectable chondroprotector. At the same time, the patient has the opportunity to take these drugs in tablets in a comfortable home environment, there are no painful sensations from injections, and there is no need for medical staff to carry out the procedure. And the cost of a course of taking Chondromarin for 1 month is much lower than the cost of a course of injection procedures.

Chondroprotectors for joints - list

There are many different means and commercial offers on the market. We sell the following items:

Chondromarin is a drug that restores cartilage. Thanks to subtilisins (enzymes) in its composition, it eliminates chronic inflammation, as a result of which the pain syndrome subsides. It can be used in sports with high loads on the joints, as well as for arthrosis, arthritis, osteochondrosis, and joint injuries. Composition: oligonucleotides, chondroitin sulfate, glucosamines, collagen, enzymes, amino acids (biologically active substances of salmon cartilage). The package contains 70 capsules, designed for a monthly course.
Chondromarin Cryptos is a regenerative drug that intensively restores and rejuvenates cartilage and bone tissue. To restore bone and cartilage after injuries and diseases, a person needs his own osteoblasts, which are produced by the bone tissue itself. In adults, active osteoblasts are no more than 10%: the remaining 90 percent turn into osteocytes, which are only able to maintain bone metabolism and no longer take any part in its rejuvenation or restoration. Chondromarin Cryptos activates the work of osteoblasts, and also increases the supply of young osteoblast bone cells by creating them from pluripotent progenitor cells. Consists of minerals and proteohycans, which are thoroughly protected by Axis technology from destruction in the gastrointestinal tract. It is used as a prophylaxis of age-related changes. The package contains 10 capsules, designed for 1 month of intake (1 capsule every 3 days). Use either simultaneously or AFTER a course of Chondromarin (70 capsules).
Supercalcium - contains biologically active, easily digestible calcium and natural (not synthesized) vitamins D3, B1, B2, B3, A, E, C. It also contains nicotinic acid and trace elements: silicon, phosphorus, manganese, zinc, iron, iodine, selenium and others. The preparation is processed according to Axis technology, which increases the degree of application efficiency by an order of magnitude. The package contains 30 capsules.

How to enhance the effect

Taking chondroprotectors for the joints and following the following recommendations, you can significantly increase the effectiveness of the drugs.

if you have extra pounds, consult a nutritionist and adjust your diet. When body weight decreases, pain will decrease;
do exercise therapy lying down or sitting. Attention: it is necessary to load not the articular cartilage, but the muscles near it;
rest more: for an hour of activity there should be 15-20 minutes of rest;
walk: even 20 minutes a day will be useful;
go in for swimming and exercises in the water: this allows you to give a load to the muscles, and not to the joints;
do not overcool.

Indications for use

Chondroprotectors are used in the following situations:

arthritis, in particular - giving complications to the bone tissue;
spondylosis;
arthrosis, coxarthrosis;
bruises, sprains, dislocations;
joint injuries, spinal injuries.

Chondroprotectors for new generation joints are often used as a preventive measure. It is especially important to use chondroprotectors for athletes with increased stress on the joints. This allows you to protect and preserve the joints from premature wear and tear.

Chondroprotectors are also used for recovery after joint surgery.

For osteoarthritis of the knee

In arthrosis of the knee joint, intra-articular injections are very popular. Local injections quickly reduce inflammation and restore mobility. As a rule, a course is required: 7-10 injections in each joint. It hurts and many patients are afraid of these injections. Chondroprotectors Chondromarin and Chondromarin Cryptos are an alternative to injections.

With osteochondrosis of the spine

Chondroprotectors cannot be called the main tool in the fight against osteochondrosis, the role of physical exercises is very important here. But as a complex additive, they are used regularly. These drugs can be especially useful with increased stress on the spine and with spinal injuries. Dietary supplements chondroprotectors significantly reduce the recovery time for damaged joints.

Chondroprotectors for athletes

The funds are recommended for admission to those who regularly engage in physical activity. They are suitable for both professionals and those who only occasionally visit the gym. Chondroprotectors for athletes are excellent support and protection of joint tissues. They nourish cartilage and protect it from premature destruction. Sports doctors recommend taking such drugs to almost all athletes. Chondroprotectors are especially relevant in sports among bodybuilders and weightlifters, as well as wherever there is an increased load on the joints.

Chondroprotectors for spondylosis

Chondroprotectors for spondylarthrosis are prescribed if the symptoms of the disease are already disturbing, but the disease has not yet reached a critical stage requiring surgery. Chondroprotectors slow down the deformation of cartilage tissue. They give rise to the emergence of new formations in the articular tissue, slow down the degeneration of cartilage, and accelerate the formation of joint fluid.

How to choose

When choosing a dietary supplement, carefully study the instructions. If you choose between the chondroprotectors presented on our website, then you should start taking the course with Chondromarin, and only then you can move on to Chondromarin Cryptos. The number of packages should be taken at the rate of "1 package of the drug is a course of admission for 1 month."

If you need a chondroprotector as a source of calcium, then in this case you need to choose the dietary supplement Supercalcium.

The selection takes into account the individual characteristics of the patient. In autoimmune diseases (including arthritis), the dosage of Chondromarin should be less than the standard recommendation for "almost healthy" people. It is advisable to consult in advance.

How to use

Take on an empty stomach: half an hour before a meal, or 2 hours after a meal. Be sure to drink water (50-100 ml of water).

Preparations Chondromarin and Chondromarin Cryptos should be taken separately from calcium preparations, since joint use can deactivate (neutralize) their action. The break between taking Chondromarin and calcium preparations should be at least 2 hours.

Calcium preparations (including Supercalcium) are taken at night after 19-00, this is the best time for their effective absorption by the body.

1 pack of Chondromarin is a course for 1 month. At the end of the package, you should take a break of 7-10 days, after which you can repeat the course. This chondroprotector has a prolonged action, and continues to "work" during the break.

How to order

We will be happy to help you with the choice of goods.

Delivery of orders is possible to any city in Russia and even abroad.

For orders in Russia, payment is possible upon receipt of the order. Do you have any questions? Contact us and we will tell you how to order chondroprotectors in your city.

Dear friends, hello!

After a short break, we return to the conversation about drugs, and today's conversation will be devoted to a group that causes a lot of controversy. We will talk about chondroprotectors.

Throughout the past week, I have been studying this issue and came to the conclusion that modern chondroprotective drugs are still a “dark horse”.

But one thing is clear: the whole people is divided in relation to this group into 2 camps. And they all share:

Doctors. Some consider chondroprotectors to be the main pathogenetic treatment for arthrosis. Others say that this is pure profanity. The latter, in particular, include your beloved Elena Malysheva, who from the big podium, or rather, directly from the TV, said that chondroprotectors are drugs with unproven effectiveness.
Pharmacy staff. Some, having read publications and clinical studies, think the same way as a TV star. Others argue that chondroprotectors really work. This, firstly, is said by grateful customers, secondly, “I took it myself, it became easier”, thirdly, “I gave it to my mother, there is an effect.”
Sufferers who know what it is, firsthand. Some write reviews like: “drank, it’s no use. Just wasted money." Others retort them: “But it helped me!”

After studying and comprehending the videos, clinical studies and the opinions of doctors, I formed my own opinion.

CHONDROPROTECTOR DRUGS WORK, unless…

Although no, we will not run ahead of the locomotive.

I feel now how happy the supporters of this group were, and how their opponents frowned, dreaming of throwing rotten tomatoes at me.

Do not order to execute, order to say a word!

Moreover, it is in your own interests to fall in love with this group of funds: otherwise, how are you going to sell them?

We will now consider the following questions:

Why don't chondroprotectors always help?
How do they share?
Why do they have side effects?
Which is better: a single drug or a combination drug?
What are the features and "chips" of popular chondroprotectors?

But first, as usual, let's remember how the joint is arranged in our body, and due to what it works.

How is the joint arranged?

So, the joint is a connection of articular surfaces of bones, each of which is covered with cartilage.

The joint is enclosed in a joint bag, or capsule, which is attached to the articulating bones. It provides tightness of the joint and protects it from damage.

The cartilage of the joint is a kind of gasket that is necessary for the smooth sliding of the heads of the bones relative to each other and for absorbing the loads that the joint experiences during movement.

Between the heads of the bones is a slit-like space - the joint cavity.

The inner lining of the joint capsule is called synovial and produces synovial fluid into the joint cavity.

Synovial fluid is needed to lubricate the articular surfaces of the bones, so that the cartilage does not dry out, and for all the functions of the ship to work properly.

Cartilage resembles a sponge in its structure: when loaded into the joint cavity, synovial fluid is released from the cartilage, and as soon as the compression has stopped, the fluid returns back to the cartilage.

What is articular cartilage made of?

Cartilage is made up of collagen fibers that run in different directions to form a network. The mesh cells contain proteoglycan molecules that hold water in the joint. Therefore, cartilage is approximately 70-80% water.

Proteoglycans are made up of protein and glycosaminoglycans.

Glycosaminoglycans are carbohydrates, which include hyaluronic acid and chondroitin sulfate, among others. Look at the picture above: chondroitin is the brush hairs in proteoglycans.

Both require glucosamine to produce. It is formed by cartilage tissue cells, chondrocytes, from substances that enter the body with food.

In other words, glucosamine is the building block for chondroitin. And chondroitin is needed for the synthesis of hyaluronic acid.

What is synovial fluid?

It is a blood plasma filtrate, which contains hyaluronic acid, obsolete joint cells, electrolytes, proteolytic enzymes that destroy old proteins.

Hyaluronic acid binds and retains water in the joint cavity, due to which the synovial fluid moisturizes the articular surfaces of the bones, and they move relative to each other like clockwork.

And one more important point. The fluid in the joint cavity is not worth it, as in a swamp.

She circulates. Old cells die, new ones are born, the blood plasma filtrate is renewed, and for this process, like air, movement is necessary.

How is the joint fed?

The nutrition of the joint leaves much to be desired.

It has no independent blood supply.

Its "nurse" is the synovial fluid, from where the cartilage, through osmosis, that is, leakage, takes the nutrients it needs. And they enter the synovial fluid from the blood vessels passing near the joint.

But even here it is not so simple.

The cartilage absorbs the synovial fluid only during movement: the leg was bent, the synovial fluid came out of the cartilage into the joint cavity, straightened it went back into the cartilage, delivering the necessary “food” to it.

When moving, the muscles that attach to the elements of the joint contract, and due to this, blood is pumped through their vessels, delivering more nutrients to the cartilage.

More about chondrocytes

Chondrocytes are involved in the restoration and production of substances necessary for cartilage. But the whole problem lies in the fact that there are very few of them: only 5%, and everything else (95%) is cartilage matrix (collagen fibers).

In addition, among chondrocytes there are young, mature and aged cells. The parade is commanded, of course, by mature people. Others either STILL do not have enough strength to synthesize the substances necessary for cartilage, or ALREADY do not have enough.

But with adequate loads and normal nutrition of the joint, this is enough.

conclusions

Thus, for the normal operation of the joint, you need:

Mature chondrocytes receiving adequate nutrition.
Normal blood supply to the joint.
Adequate work of the muscles surrounding the joint.

Why does arthritis develop?

It most often develops as a result of one of four problems:

Or they overloaded the joint (excess weight or sports loads that exceed the ability of the cartilage to extinguish them).
Or they didn’t load it (physical inactivity, as a result of which the blood supply to the joint is disturbed, the cartilage does not receive adequate nutrition and begins to collapse).
Or all together (+ hypodynamia).
Or a serious injury in which the metabolism in the joint and its nutrition are disturbed.

What happens in the joint under the influence of these factors?

Chondrocytes do not have time (with OVERLOAD) or cannot (with UNDERload) form a sufficient amount of glucosamine.
If there is no glucosamine, chondroitin is not formed.
If chondroitin is not formed, hyaluronic acid is not formed.
If hyaluronic acid is not formed, fluid is not retained in the joint.
If there is little fluid in the joint, the articular heads of the bones are not moistened.

And then this is what happens:

Stages of arthrosis

Stage 1 arthrosis:

Cartilage loses water, i.e. dries up.
Collagen fibers are torn or completely destroyed.
The cartilage becomes dry, rough and cracks.
Instead of sliding freely, the cartilages of the articulating bones "cling" to each other.

Stage 2 arthrosis:

The pressure on the bone increases.
The heads of the bones begin to gradually flatten out.
The cartilage thins out.
The joint space is reduced.
The joint capsule and synovial membrane "wrinkle".
Bone outgrowths - osteophytes - appear along the edges of the bones.

Stage 3 arthrosis:

The cartilage disappears completely in places.
The bones begin to rub against each other.
The deformity of the joint increases.

Stage 4 arthrosis:

The cartilage is completely destroyed.
The joint gap is practically absent.
The articular surfaces are exposed.
The deformity of the joint reaches its maximum.
Movement is not possible.

As a result of these changes, inflammation develops in the joint. It becomes edematous, but intensifies.

Now let's move on to the drugs.

But first, a few basics.

When do chondroprotectors "work"?

First of all, let's clarify the following for ourselves:

Chondroitin and glucosamine are effective on 1-2 stages of arthrosis, when there is no cartilage destruction yet, and chondrocytes are alive.
Chondroitin sulfate is a large molecule, about 100 times larger than glucosamine, so its bioavailability is only 13%.
The bioavailability of glucosamine is greater, but also not much, only 25%. This means that 25% of the dose taken will reach the joint directly.
The optimal therapeutic dosages of chondroprotectors for oral administration, according to practitioners, are as follows:

To get real results, you need 2-3 courses of treatment with these drugs, which will take up to 1.5 years.
Practitioners advise taking chondroprotectors continuously for 3-5 months and repeating the course every six months.
Chondroprotectors should be taken regularly, in courses, and not on a case by case basis.
It is pointless to take chondroprotective drugs if you continue to mock the joint with excessive loads. To achieve the effect, you need to reduce weight, and athletes abandon conventional training.
You can take this group for a very long time and not see the result if you do not provide normal nutrition to the joint. This requires special (!) Exercises.
For the production of chondroitin and glucosamine, cartilage of cattle, extracts from marine fish are used. It is difficult to achieve 100% purification, therefore, when taking these drugs allergic reactions occur and problems from the gastrointestinal tract (abdominal pain, diarrhea, constipation, etc.).
Chondroitin sulfate reduces clotting blood, so it can not be used together with anticoagulants and with a tendency to bleeding.

contraindicated

Diabetics when taking these drugs need to carefully control their sugar levels. It can rise (carbohydrates after all).

How do chondroprotectors work?

What does glucosamine do?

Stimulates the activity of chondrocytes.
Necessary for the synthesis of chondroitin sulfate and hyaluronic acid.
Prevents the destructive effect on the cartilage of NSAIDs and glucocorticosteroids.

What does chondroitin sulfate do?

Necessary for the synthesis of hyaluronic acid.
Normalizes the production of synovial fluid.
Reduces the activity of enzymes that damage cartilage.
It has an anti-inflammatory effect.

Types of chondroprotectors

Let's analyze how chondroprotectors are divided.

According to the way of taking exist:

Preparations for oral administration (Struktum, Dona powders and tablets, Artra, etc.)
Preparations for injections (Dona r / r, Alflutop, Rumalon, etc.)
Preparations for external use (Chondroxide, Chondroitin, etc.).

With parenteral administration, the bioavailability of chondroprotectors is significantly higher, so they are prescribed when you need to quickly relieve an exacerbation, or when the patient prefers short courses of treatment, or when there are problems with the liver, so as not to burden it.

Preparations for external use are effective only in combination with other forms of release.

By composition, chondroprotectors are divided into:

Monopreparations that contain only chondroitin sulfate (CS) or glucosamine (GA): Structum, Don.
Combined products containing both one and the other component: Artra, Teraflex.
Means that, in addition to cholesterol and GA, contain a non-steroidal (i.e., non-hormonal) anti-inflammatory agent: Teraflex Advance.

With the latter, everything is clear: if there are signs of inflammation (severe pain, swelling), at first we recommend a drug with NSAIDs. After 2-3 weeks, you can switch to a "clean" chondroprotector.

As for the first two, there is no unequivocal answer to the question “which is better”. Some doctors prefer single drugs, others combined, and still others prescribe both, depending on the situation.

But I noticed that glucosamine gives more side effects from the gastrointestinal tract.

Therefore, the combination of GA and CS seems to me the most optimal: it increases the bioavailability of the drug and reduces the frequency of adverse reactions.

Well, now let's go over the drugs.

I'll start with the "oldies":

RUMALON- solution for intramuscular injection.

Compound:

Glycosaminoglycan-peptide complex derived from cartilage and bone marrow of calves (powerful allergen due to animal proteins).

What is he doing:

It improves the synthesis of cholesterol, promotes the maturation of chondrocytes, stimulates the synthesis of collagen and proteoglycans. Moreover, the manufacturer writes that the drug is effective both in the early and late stages of arthrosis. The latter makes me doubt.

Application: administered according to the scheme for 5-6 weeks, 2 times a year.

Side effects: allergic reactions.

ALFLUTOP- injection.

Ingredients: bioactive concentrate from small marine fish.

Contains amino acids useful for cartilage, mucopolysaccharides, trace elements: sodium, magnesium, zinc, iron, etc.

What it does: It inhibits the activity of hyaluronidase, an enzyme that breaks down hyaluronic acid. So the latter becomes larger, and the condition of the cartilage improves.

Application:

There are 2 ways to use it:

Intramuscularly daily 1 ml for 20 days.
Intra-articular 1 or 2 ml per joint every 3-4 days. Only 5-6 injections.

The course is repeated after six months.

Sometimes doctors start with intra-articular injections, then move on to intramuscular injections. It depends on the doctor. How many doctors, so many methods.

Contraindications: Allergy to seafood (sometimes very strong).

CHONDROLONE- lyophilisate (i.e. the active substance is in a dried state) for the preparation of a solution

Composition: contains chondroitin sulfate 100 mg per ampoule.

Since the bioavailability is high with this administration, this dosage is sufficient.

It is obtained from the cartilage of the trachea of cattle.

What it does: inhibits the activity of enzymes that cause cartilage destruction, stimulates the production of glycosaminoglycans by chondrocytes, normalizes the production of synovial fluid, and has an anti-inflammatory effect.

Application: in / m 1-2 ampoules every other day. Only 25-30 injections. The course is repeated after six months.

DONA- monopreparation.

Ingredients: contains glucosamine sulfate.

What it does: stimulates the synthesis of hyaluronic acid and other glycosaminoglycans, inhibits enzymes that cause cartilage destruction.

In one tablet 750 mg HA.

How to take: 1 t. 2 times a day with meals. Improvement occurs in 2-3 weeks. The minimum course is 4-6 weeks. Repeat the course after 2 months.

The powder contains 1500 mg of HA.

For whom is it optimal this form of release: powders are especially good for working citizens who find it more convenient to take the drug only 1 time per day.

And also for those who have difficulty swallowing tablets.

Application: the powder is dissolved in a glass of water and taken 1 time per day (also better with meals). The course is 6 weeks, repeated after 2 months.

Solution for i / m administration: in 1 ampoule 400 mg of glucosamine. Bioavailability 95%. In addition to glucosamine, it contains lidocaine, therefore it has many contraindications: cardiovascular insufficiency, impaired liver and kidney function, epileptic seizures, etc. There are many side effects.

Medical prescription only!

Application: Enter 3 times a week for 4-6 weeks. And then as the doctor decides. Maybe he will switch to powders or tablets.

STRUKTUM- capsules.

Ingredients: contains chondroitin sulfate.

There are 250 mg and 500 mg. To be honest, I don’t know why the first form of release exists, since the manufacturer recommends taking 500 mg 2 times a day.

Judging by the presence in Moscow pharmacies, Structum 250 mg is leaving the shelves. Maybe I'm wrong.

What is he doing? Stimulates the synthesis of glycosaminoglycans, improves the metabolic process in the cartilage.

Application: take it 500 mg 2 times a day for 6 months.

The action after cancellation lasts 3-5 months, then you need to repeat the course.

- combined remedy.

Composition : contains very adequate dosages of chondroitin and glucosamine: 500 mg each

What it does: All the good things HA and CS do in the joint.

Application: take this drug 1 ton 2 times a day for the first 3 weeks, then 1 ton a day for a long time, but not less than 6 months.

TERAFLEX ADVANCE - another combination drug.

Composition: it contains: GA 250 mg, cholesterol 200 mg and ibuprofen 100 mg.

So, in addition to all the beneficial effects of the first two substances, it also has an anti-inflammatory and analgesic effect.

In addition to all the beneficial effects of the first two substances, it also has an anti-inflammatory and analgesic effect.

True, contraindications and side effects due to ibuprofen become several times larger.

Application: take it 2 capsules 3 times a day after meals for no more than 3 weeks. Then they switch to the usual Teraflex.

TERAFLEX

Composition: contains GA 500 mg, cholesterol 400 mg.

Application: take it for the first 3 weeks, 1 capsule 3 times a day, then 1 capsule 2 times a day for 3-6 months, preferably with meals. Then, as usual, the course is repeated.

External chondroprotectors

Here I will focus only on the most popular drug Chondroxide.

CHONDROXIDE

Composition: contains 1 g of 50 mg of chondroitin sulfate.

Release form: ointment and gel.

Application:

A large molecule of chondroitin cannot penetrate the skin on its own, therefore, in order to pass it through cell membranes, dimexide is added to the drug, which also has an anti-inflammatory and analgesic effect.

Do not apply to open wounds.

CHONDROXIDE FORTE – cream

Composition: contains cholesterol and the anti-inflammatory substance Meloxicam, that is, it reduces inflammation and pain.

Contraindications standard for NSAIDs.

Given this composition, it is better not to advise the elderly. For them, there is a gel for the period of exacerbation.

This is not just a cream, it is a transdermal glucosamine complex (glucosamine + triglycerides).

Compound . contains glucosamine, and not chondroitin, like the previous forms, and dimexide, so we recommend it when an allergic reaction to other external forms of chondroxide has been noted in the past.

And also when the buyer does not care about the high price. The main thing is that the effect is maximum.

The active substance is enclosed in a shell of lipids, which together form a micelle (nanoparticle), which delivers the active substance to the joint in a concentration comparable to an injection.

Application: apply it 2-3 times a day for 3-4 weeks. If necessary, the course is repeated.

I end with this.

You have a lot of chondroprotectors in your assortment: both drugs and dietary supplements.

But knowing the basic things that I talked about, you can now independently understand the composition of such a tool and its effectiveness.

I hope that now you can easily continue the phrase:

CHONDROPROTECTORS WORK, unless…

And as a homework, I suggest you think about:

What questions should a buyer ask when choosing a chondroprotector?

Having studied everything thoroughly, I understood why in some countries all chondroprotectors are considered additives: because their bioavailability is low (and manufacturers, by the way, do not hide this), and the therapeutic effect is greatly delayed in time.

And in conclusion, I will answer the most common question:

Why are there many bad results of using chondroprotectors?

Because, as usual, people are hoping for a magic pill without putting in the effort to lose weight and work muscles.
Because they want quick results, and not seeing them, they stop treatment.
Because they begin to "drink Borjomi when the kidneys have failed", i.e. take chondroprotectors at 3-4 stages of arthrosis.

That's all.

How did you like this article, friends?

What do you think about chondroprotectors YOU?

Add, comment, share your experience, click on the social buttons. networks.

See you on the blog for hard workers!

With love to you, Marina Kuznetsova

Chondroprotectors are drugs aimed at preserving and restoring the bone tissue of the joints. These medicines are classified as long-acting medicines. For example, the effect of treatment with chondroprotectors of the spine appears only after a certain period of time. Medicines of this group in each case can be purchased only on prescription.

General information

These medications contain glucosamine and chondroitin sulfate. These substances stop the dystrophic processes that occur in the body and normalize damaged bone tissue.

In addition to active substances, vitamins, minerals and antioxidants are included in the new generation chondroprotectors for the spine. All of them have a complex effect on problem areas in the joints and prevent subsequent destruction of bone tissue.

Main types

To understand what are the most effective chondroprotectors for the spine, it is necessary to fully explore the range of funds that belong to this group. Doctors classify drugs into several types.

The first is Rumalon and Alflutol.
The second is drugs that are developed on the basis of glucosamine and hyaluronic acid.
The third is the means where the active element is chondroitin sulfate.

Taking into account which main active ingredient is included in the composition of the chondroprotector, the pharmacological effect differs from the drug. It is impossible to choose the best chondroprotector for the spine on your own. The prescription of the medicine must be entrusted to a professional doctor who, after diagnosis, will be able to develop a comprehensive treatment regimen.

According to the method of application of the drug can be:

For oral use (Piaskledin, Structum, Artra). The result of the therapy can be observed after 10-12 weeks, but a steady relief of the condition occurs only after 6 months. The tablet form is well tolerated and causes almost no side effects.
For injection use (Noltrex, Adgelon, Alflutol). The result can be observed after 4-5 weeks. The effect of the drug lasts for a short time, so the therapy is repeated every 6 months.
Analogues of intra-articular injections (Synvisk, Ostenil, Synocrom). They are administered intra-articularly and are used to restore synovial fluid during its shortage. The complex of treatment consists of 4-6 injections. This, as a rule, is quite enough to obtain a pronounced and stable effect. Re-treatment is performed after 6 months.

A number of factors can influence the choice of medication. Among these are the progression of the disease, the volume of synovial fluid, the condition of the joints.

Operating principle

To determine the best chondroprotector for yourself, you need to know what specific effect each of them has on the joints. The effectiveness of the drug is aimed at getting rid of the causes that caused the pathology.

Chondroprotectors act in this way:

Contribute to the reduction of doses of the use of anti-inflammatory non-steroidal drugs.
Restore joints.
Reduce inflammation and relieve pain.

After using the drug, the active element is absorbed into the blood and localized in the area of the articular tissue. But certain drugs can hardly overcome barriers in the form of cellular barriers, so additional measures will be required.

The main active ingredients, accumulating in the body, remain effective for several months. This allows you to make small breaks between therapeutic courses.

Side effects while taking chondroprotectors are quite rare, therefore, with a significant damage to the cartilage, the doctor can prescribe several drugs of this group at once. This approach makes it possible to significantly increase the effectiveness of the drugs used, but their compatibility must be taken into account.

Features of treatment

In each specific case, the drug has its own effect. During the treatment of one pathology, the drug shows a high result, and during the other - insufficient.

The list of chondroprotectors in terms of effectiveness can only be compiled individually for each specific patient. To begin with, it is necessary to take into account the stage and type of the degenerative process.

Drugs for coxarthrosis

This pathology is characterized by physical deterioration of the structures of the hip joint, which limits its work.

In this case, drug treatment involves the use of chondroprotectors, which contain chondroitin sulfate and glucosamine as active elements.

The best remedy for the treatment of coxarthrosis is Teraflex. The drug quickly restores metabolic processes, which allows you to normalize cartilage structures. This is due to the formation of a healthy matrix, which makes it possible to protect the joints from deformation. Drug treatment carried out with this medicine will require almost no additional use of NSAIDs.

Also, coxarthrosis therapy is often carried out with the help of Chondroxide. The main effect of the tablets is aimed at activating metabolic processes in the area of the articular bag. The medicine restores metabolic processes in the area of cartilaginous tissue, enriching it with the required substances for normal operation.

Medicines for osteochondrosis

During osteochondrosis, deformation of the intervertebral discs occurs.

For the treatment of this disease, chondroprotectors are used, the action of which is aimed at normalizing the condition of the joints and bone tissue, as well as reducing pain.

Effective treatment of osteochondrosis can be carried out with the help of Don, Artra and Structum preparations. The sooner you start a therapeutic course, the faster the effect will come. During an advanced disease, it is almost pointless to use chondroprotectors.

To increase the effectiveness of therapy, it is advised to use complex treatment. Quite often, non-steroidal drugs (Diclofenac, Voltaren, etc.) are used.

Getting rid of arthrosis

During the development of arthrosis, chronic degenerative processes in the area of the joints are noted.

With this pathology, the effect of chondroprotectors is in question. Most doctors say that it is impossible to do without these drugs, while other experts say that there is no point in such therapy. As a result, after the studies, it was found out: a positive trend is observed only at the beginning of the progression of the disease or provided that the chondroprotectors are taken by the patient for a long time.

Particularly effective means in the treatment of arthrosis are Artron flex, Dona, Teraflex. With their help, you can restore the concentration and volume of synovial fluid.

Remedies for arthritis

This inflammation is characterized by malnutrition of the joints with substances required for the normal functioning of the joint. During arthritis, it is advised to use chondroprotectors simultaneously with painkillers and anti-inflammatory drugs.

Among the most effective drugs, one can note those where the active components of chondroitin sulfate and glucosamine are included: Structum, Artron, Chondroxide. This approach to treatment makes it possible to get rid of pain and swelling, as well as restore joint mobility.

Combined and single-component medicines

Preparations are considered combined if they contain two or more main active ingredients. Nevertheless, drugs with one main active substance are often sufficient for treatment. The best of the complex and monocomponent chondroprotectors are:

Artra. The most popular remedy that is most often used during the treatment of arthritis and osteochondrosis. The drug is based on glucosamine and chondroitin sulfate. This medicine is not recommended for children under 16 years of age, as well as for people who have kidney and liver failure. The tool is suitable for patients suffering from diabetes and asthma.
Formula-C Combined drug, which is prescribed for the treatment of arthritis, osteochondrosis and arthrosis. It is advised to use it for patients with joint injuries. The tool effectively relieves pain without the additional help of other drugs, accelerates the recovery of joints. The drug has practically no contraindications and is used for a long time (at least 3 months).
Teraflex. The active substances are chondroitin sulfate and glucosamine. The drug gives the desired effect only in the initial stages of joint diseases. It is often prescribed during joint injury and for the treatment of osteochondrosis and arthrosis. The medicine is not recommended for people with phenylketonuria. Doses must first be agreed with a specialist, otherwise an allergy may occur.
Structum. A medicine containing the active element chondroitin sulfate. It is used to combat arthrosis and osteochondrosis. A relative contraindication is the development of thrombophlebitis. Dosage advice is given only by a doctor after examinations and diagnosis.
Don. Means with glucosamine sulfate as the main substance. The drug restores the processes of supplying the joints with nutrients and is recommended to combat osteochondrosis and arthritis. The drug is administered intravenously or taken orally. The doctor calculates the dose taking into account the stage of the disease.

Therapy with natural substances and products

The active elements in the natural chondroprotector Alflutol are extracts from Black Sea fish. The action of the drug is aimed at restoring metabolic processes and relieving inflammation in the joints. The main indications for use are osteochondrosis, spondylosis, arthrosis. The tool is used in the period after the operation. Among the side effects can be noted pain in the joints and muscles after injections. The approximate course of treatment is one month.

A lot of useful substances that take part in the restoration of bone tissue are also found in certain products. It is for this reason that in diseases of the musculoskeletal system, it is necessary to include food enriched with natural chondroprotectors in the daily menu - stew, strong broths, beans, avocados, jelly and aspic.

Among the most effective natural elements that act as chondroprotectors, we can note:

Chondroitin sulfate. Reduces the activity of hyaluronidase, which breaks down the intercellular fluid, and increases the amount of synovial substance, which allows you to nourish the joint. The natural chondroprotector chondroitin has a pronounced and stable anti-inflammatory and analgesic property.
Glucosamine. This substance is the most important intercellular element of the joints, increases the content of proteoglycans and collagen in the body. Protects the joints, preventing their destruction.
Hyaluronic acid. This substance normalizes metabolic processes in the area of the joints, reduces the degenerative process. Hyaluronic acid is an element of the intercellular articular substance.

In order for drug treatment to have a positive effect, certain recommendations must be followed. The main advice of doctors is as follows:

To increase the effectiveness of the treatment course, chondroprotectors should be used simultaneously with nonsteroidal agents and physiotherapy.
The use of chondroprotectors is possible only as directed by a doctor after a complete diagnosis.
To restore a deformed joint, you need to spend at least 5 courses of treatment with chondroprotectors.
You can not arbitrarily complete therapy after the disappearance of the symptoms of the disease. The treatment course must be completed in full.
It is forbidden to give an excessive load on the damaged joint and allow hypothermia.
It is necessary to perform special exercises daily.
Get rid of excess weight (if any).

You can read a lot of positive reviews from patients who are convinced that it was chondroprotectors that helped them completely recover from the disease. But there are also negative opinions, when patients say that these drugs are completely useless. All this in most cases indicates that it is not necessary to self-medicate with the help of chondroprotectors. But if the doctor prescribes these drugs, then the recommendations cannot be neglected.